The Rabbit Anti-papillomavirus type 18 Regulatory protein E2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Virus antigen. The Rabbit Anti-papillomavirus type 18 Regulatory protein E2 Antibody has been validated for the following applications: EIA, Immunoassay, and ELISA.
Description
E2 regulates viral transcription and DNA replication. It binds to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory region. It can either activate or repress transcription depending on E2RE's position with regards to proximal promoter elements. Repression occurs by sterically hindering the assembly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication